Botox is a medical procedure used in the treatment of specific muscular conditions, and a cosmetic approach for the removal of wrinkles by paralyzing muscles for a short period. Botox is created from botulinum toxin, a neurotoxin produced by the bacterium Clostridium botulinum.
Botox is a fantastic poison when applied correctly; it can be used in several ways.
This article will give you an in-depth understanding of how the process works, the purpose of Botox, and the perils of using Botox.
QUICK FACTS ABOUT BOTOX
• Presently, Botox is the most renowned non-surgical cosmetic treatment procedure as there are more than six million Botox treatments offered every year.
• As a neurotoxin, Botox is obtained from Clostridium botulinum, an organism discovered in the natural location where it is inactive and non-toxic.
• It can be used for the reduction of fine lines and wrinkles by weakening the core muscles.
• Individuals use Botox for the treatment of extreme sweating, bladder and bowel disorders, as well as muscular disorders.
• Botulism is a health disorder caused by botulinum toxin can trigger respiratory failure and can be terminal.
• One gram of botulinum toxin is capable of killing one million individuals. Two kilograms can wipe out the whole human population on Earth.
WHAT IS BOTOX?
Botox is obtained from a bacterium called Clostridium botulinum; it is usually discovered in most natural locations such as lakes, forests, and soil.
The bacterium can also be discovered in the intestinal tracts of mammals and fishes, and the organs and gills of crabs and other shellfish. These naturally occurring examples of Clostridium botulinum bacteria and spores are usually safe. There are issues when these spores change into vegetative cells, and this brings about an increase in the cell population. The bacteria will start the production of botulinum toxin, the poisonous neurotoxin causing botulism at a specific point.
These neurotoxins focus on the nervous system and upset the signaling procedures that enable effective communication of the neurons.
FUNCTION OF BOTULINUM TOXIN
Botulinum toxin remains one of the most toxic substances man has ever known. According to scientists, a single gram of this poisonous substance has the power to kill one million individuals and two kilograms can also wipe out the entire human existence on planet earth. If it is available in higher proportions, botulinum toxin can cause botulism, a terminal health disorder. If left unattended to, botulism can cause respiratory failure and the death of the patient. Despite the toxicity of botulinum toxin, Botox sells like hotcakes.
It is also ironical that the botulinum toxin has been certified to be a reliable and effective healing protein. The Botulinum toxin can be inserted into the bodies of human beings in small concentrations, and it works by inhibiting the signals from the nerve cells connected to the muscles thereby crippling them.
The nerves discharge a chemical messenger, acetylcholine (a neurotransmitter), to enable the contraction of the muscles at the point where the nerve endings connect with the muscle cells. Acetylcholine attaches to the receptors on the muscle cells and triggers the muscle cells to reduce or shrink.
Vaccinated botulinum toxin averts the discharge of acetylcholine, foiling the withering of the muscle cells. It is responsible for a reduction in abnormal muscle contraction enabling the muscles to be less hardened.
USES OF BOTOX
• With the application of Botox injections, cosmetic surgery can be done.
• Botox is a popular cosmetic procedure used for the improvement of the appearance of wrinkles and fine lines.
• Botulinum toxin is used mainly as a treatment plan for the reduction of the presence of fine lines and facial wrinkles.
• It is also used as a treatment alternative for the treatment of more than twenty health disorders, with more applications under review.
• Apart from appealing applications, Botox can be used for the treatment of medical conditions such as migraines, extreme sweating, eye squints, and loose bladders.
• Botulinum toxin is presently certified for the following healing applications:
• Eyelids spasm (Blepharospasm)
• A chronic Migraine
• Idiopathic rotational cervical dystonia (severe neck and shoulder muscle spasms).
• Excessive sweating; severe primary axillary hyperhidrosis.
• Strabismus (crossed eyes)
• Post-stroke upper limb spasticity.
• Detrusor (bladder wall muscle) overactivity – causing urinary incontinence.
• Overactive bladder.
• Hemifacial spasm.
• Glabellar lines (frown lines between the eyebrows).
• Canthal lines (crow’s feet).
However, Botulinum toxin is also applied off-label, but not certified for the treatment of the following:
• Achalasia, a health condition associated with the throat which makes swallowing hard.
• Anal anismus and fissure (malfunctioning of the anal sphincter)
• Sialorrhea( production of excessive saliva)
• Hay fever( allergic rhinitis)
• Sphincter of Oddi (hepatopancreatic) dysfunction which is responsible for abdominal pain.
• Cerebral Palsy.
• Oromandibular dystonia (muscular contraction of the jaw, face, and/or tongue).
• Laryngeal dystonia (forceful contraction of the vocal cords).
Botulinum toxin is available in commercial quantities under the following names:
Botox, Vistabel, Botox cosmetic (OnabotulinumtoxinA or botulinum toxin type A)
Dysport (AbobotulinumtoxinA or botulinum toxin type A)
Bocouture, Xeomin (IncobotulinumtoxinA or botulinum toxin type A)
Myobloc (RimabotulinumtoxinB or botulinum toxin type B).
WHAT IS BOTULISM AND HOW CAN IT BE PREVENTED BY US?
Botulism is a severe ailment caused by the botulinum toxin.
Method of Application
Botulinum toxin can be used by mixing the powder in saline and injecting the substance into the neuromuscular tissue. The Botulinum toxin usually starts taking effect on the body within 24-72 hours. However, in seldom cases, the full impact of botulinum toxin may take up to five days to be seen.
It should not be used by women who are breastfeeding their kids, and pregnant women. Individuals who have had a prior allergic reaction to the drugs or its components should not use it either.
DANGERS AND HAZARDS
The side effects of a botox injection are general malaise, double vision, migraines, and nausea.
Botulinum toxin injections are usually well tolerated, and there are few dangers in this case. However, a person may have a genetic tendency that leads to a mild, temporary unusual reaction to the drug in rare cases.
About one percent of individuals receiving the Botulinum toxin type A injections develop antibodies to the toxin that render successive treatments plan useless.
In combination with its planned impacts, botulinum toxin may trigger some undesirable outcomes which could be as follows:
• Mild Pain, local edema (fluid buildup), or skin reddening known as erythema at the injection point.
• A headache
• Malaise- not feeling well most times
• Mild nausea
• Short-term undesirable weakness/ paralysis of close muscles.
• Drooping, a case of temporary upper lid or brow ptosis.
• The feebleness of the lower eyelid or lateral rectus ( a muscle in charge of eye movement)
• Dysphagia- having issues with swallowing.
• Weakness of neck
• Flu-like ailments.
• Brachial plexopathy- a health disorder that affects the nerves on the side of the chest and neck.
• Malfunctioning of the gallbladder
• Double vision (Diplopia)
• Excessive bleeding
• Blurred vision
• Reduced eyesight
• Dry mouth
• General weakness
The fame of Botulinum toxin has grown significantly in recent times, with the cosmetic minimally-invasive botulinum toxin type A procedures growing at 700 percent since 2000 to 6.3 million in 2013.